CDC funds work on rapid tests for avian flu

first_imgDec 4, 2006 (CIDRAP News) – The Centers for Disease Control and Prevention (CDC) has awarded four contracts worth $11.4 million in an effort to develop a 30-minute test for H5N1 avian influenza.The CDC said it awarded the funds to spur development of tests that doctors and field epidemiologists could use to test patients for both H5N1 and other flu viruses. Currently, testing for H5N1 in the United States must be done in 1 of about 100 designated laboratories and takes from 4 to 24 hours, depending on shipping time, the CDC said.Last month the World Health Organization (WHO) listed a rapid diagnostic test as one of the top priorities in avian and pandemic flu research. The CDC said it hopes a rapid test can be ready and licensed within 2 to 3 years.”The creation of a point-of-care test to rapidly detect human cases of H5N1 avian influenza would be a major step forward in our ability to protect public health,” Health and Human Services Secretary Mike Leavitt said in a news release.The four companies, their tests, and the contract amounts are as follows:Cepheid, Sunnyvale, Calif.—GeneXPert Flu assay, $2.4 millionIquum, Marlborough, Mass.—LIAT, Lab-in-a-Tube, $3.8 millionMesoScale, Gaithersburg, Md.—Multi-Array Detection, $706,241Nanogen, San Diego—a novel point-of-care immunoassay system, $4.5 millionOver the next year, the companies will work to develop tests that can detect flu viruses and distinguish seasonal strains from H5N1 within 30 minutes, the CDC said. Existing rapid tests can tell only if a patient has a seasonal influenza A or B virus.CDC spokeswoman Christine Pearson told CIDRAP News the contracts are intended to fund the first two of five development phases.The goal for the first two phases is to produce a prototype test that can be evaluated by the CDC, said Dr. Ruben Donis, chief of the molecular virology and vaccines branch in the CDC’s influenza division. He said the agency will fund further development only if the prototype has “acceptable performance characteristics.”In a news release, Nanogen said that if the CDC funds all five development phases, the company would receive a total of about $12.5 million over the next 2 to 3 years.The four companies were chosen from 13 applicants, the CDC said. Selection criteria included the technical specifications of the test, experience in developing diagnostic tools, staff expertise, and access to labs with sufficient security to handle H5N1 viruses.The agency also promised to provide funds for a repository of influenza reagents and other materials to help in development of the tests.See also:Dec 4 CDC news releasehttp://www.cdc.gov/media/pressrel/r061204.htmlast_img read more

BOXING: Martin Murray stops Ishmael Tetteh

first_imgMartin Murray who was having his first fight under the Golden Gloves Promotions banner failed to impress as he made hard work of scoring a seventh round stoppage win over Ishmael Tetteh in a bout fought a super middleweight at Emperors Palace near Kempton Park on Wednesday night.The highly rated Englishman made a slow start through the first three rounds holding his gloves high and fighting from behind a tight defence as he won every round against the Ghanaian who was not expected to test him. Murray (74,38kg) fighting at a pedestrian pace throughout against the rather clumsy moving Tetteh (75, 38kg) left the spectators waiting for him to open up which he never did.Tetteh complained of a head butt in round five after going down on one knee in an earlier exchange which was not ruled as a knockdown by referee Thabo Spampool. It came as a surprise when Tetteh decided not come out at the bell for the seventh round as he did not appear to be in any trouble. The world rated Murray improves his record to 21-1-1; 12 and Tetteh drops to 29-11-2; 16.In the main supporting bout junior welterweight Paul Kamanga (63,45kg) from the Democratic Republic of the Congo had to come back from a rocky fifth round before stopping southpaw Adam de Moor (63.45kg) at 2:36 into seventh round. Kamanga improves his record to 11-0; 8 and De Moor drops to 10-2; 7.In a junior welterweight bout Grant Fourie (63,05kg) stopped Luyanda Jaku (63,30kg) at 2:14 of the fourth round.Heavyweight Martin Makabu (107,05kg) stopped Chris Mabombo (91,40kg) at 1;04 into the second round. Junior welterweight Boitshepo Mandawe (62,65kg) won on a fifth round technical knockout over Herbert Nkabiti (63,45kg). Time 1:05.In the opening bout of the evening super middleweights Vhonani Netshitamboni (74,95kg) and Page Tshesane (75,40kg) fought to a six round drawlast_img read more

Countryside Motors has a Halloween Costume Contest and Games Galore

first_imgHalloween Countryside storylast_img

BEAT THE BURGLARS! GARDAI TO HOLD PUBLIC MEETING IN BID TO TACKLE CRIME

first_imgGARDAI are to meet the public in a bid to stop criminal gangs.The Donegal Family Resource Centre in Donegal Town will be holding a crime prevention information evening next Wednesday, January 23 at 7.30pm.Chairman of the DFRC, Jim McLaughlin, said today: “The centre has organised a public event in order that local Gardaí can provide information to local people concerning crime prevention techniques and initiatives. “We will be discussing techniques that we can implement for our own personal protection and we will also look at the establishment of new Neighbourhood Watch and Community Alert Schemes.“This is a community response to the present crime wave which seems to be particularly aimed against our older citizens. Through this event, we hope to make people more aware of efforts and initiatives that we can all engage with. Given the continuing situation it is now crucial that we as a community look out for one another, protect each other and work closely with the Gardaí to prevent and apprehend criminals who are targeting our neighbours and friends.”The Crime Prevention evening will be addressed by representatives of An Garda Siochana at the Donegal Family Resource Centre. The event will start at 7.30pm sharp. For further information contact DFRC 074 972 5337. Advertisement  BEAT THE BURGLARS! GARDAI TO HOLD PUBLIC MEETING IN BID TO TACKLE CRIME was last modified: January 16th, 2013 by BrendaShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:BEAT THE BURGLARS! GARDAI TO HOLD PUBLIC MEETING IN BID TO TACKLE CRIMElast_img read more

Seeing the Skies Through Galileo’s Eyes

first_imgCHICAGO, ILLINOIS—When Galileo Galilei shook up the scientific community with evidence of a heliocentric world, he had a little tube fitted with two pieces of glass to thank. But just how this gadget evolved in the nascent days of astronomy is poorly known. That uncertainty has inspired a group of researchers to compile the most extensive database of early refracting telescopes to date, presented here yesterday during a poster session at the annual meeting of AAAS, which publishes Science. Now, the scientists plan to use modern optics to recreate what Galileo—and the naysaying observers of his time—experienced when they first peered through these tubes at the rings of Saturn, the moons of Jupiter, and the phases of Venus.The database, called Dioptrice, went online earlier this month. It contains records of about 1300 telescopes—mostly physical artifacts from museums and private collections, but also descriptions in books and depictions in art—that date from 1610 to 1775. Those years marked a formative period for the telescope, explains Stephen Case, a science historian and graduate student at the University of Notre Dame in Indiana who helped compile Dioptrice. For the last 2 and a half years, he has pored over books in attic of Chicago’s Adler Planetarium and tracked down telescopes in museum catalogs from galleries around the world.The first phase of the project involved documenting the origin and design of each telescope. Case and his colleagues concluded that most were used for military purposes, such as spotting distant ships or approaching troops, or were simply collected as status symbols, before they achieved widespread scientific use.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)But phase two will look deeper at the optical abilities of the telescopes. Their designers weren’t yet able to make perfectly curved class, so the lenses had jagged edges and a small field of view. And until the mass production of the achromatic lens around 1775, they couldn’t correct for the fact that different wavelength of light refract at different angles and cause a blurry image at the focal point. Yet the crude setup inspired a string of eureka moments. “Galileo suddenly could see the phases of Venus,” Case says. “He could see the moons orbiting around Jupiter. He suddenly had evidence for the heliocentric cosmology.”To precisely test how these devices transmitted distant light, the group will use adaptive optics—the technology behind today’s large telescopes. These rely on a grid of deformable mirrors that tilt to adjust for the light-bending turbulence of the atmosphere. The researchers will essentially run that process in reverse, Case says, feeding a light source with a grid structure into the telescope and observing how that grid gets distorted when passing through 400-year-old glass. If the light source is an image of Saturn or Jupiter, Case explains, you can “get out on the other end what that telescope would have shown you.”Such tests could reveal whether a given telescope could conceivably show a separation between the rings of Saturn, for example. But Case points out that what a scientist perceived in these instruments also depended on his trained eye and his sense of what to look for. In other words, no adaptive optics system can account for a given stargazer’s interpretation, or apply the Galileo filter.See more of our coverage from AAAS 2014.last_img read more